MRI contrast agent delivery using spore capsules: controlled release in blood plasma.
نویسندگان
چکیده
The exine coatings of spores can be used to encapsulate drug molecules. We have demonstrated that these microcapsules can be filled with a commercial gadolinium(III) MRI contrast agent (in this proof of concept study Gd-DTPA-BMA was used) which is slowly released in plasma due to enzymatic digestion of the capsule.
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عنوان ژورنال:
- Chemical communications
دوره 42 شماره
صفحات -
تاریخ انتشار 2009